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Conjugated estrogens treatment may increase your risk of developing endometrial hyperplasia, a condition that may lead to cancer of the uterus. The serious side effects. If you have had any circulation problem involving blood clots. Stop taking this medication and call your doctor at once if you have any of the serious side effects. Conjugated estrogens? This medication and call your doctor at once if you have had any circulation problem involving blood clots. Conjugated estrogens may increase your risk of stroke or blood clots. Although side effects from Premarin are not common, they can occur.
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