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Prednisolone is a synthetic corticosteroid which is often simply called steroid, but it may still pose a risk to the infant. Prednisone is less likely than other corticosteroids to be secreted in breast milk, but it should be ensured that if antibiotics are required, that they are given in effective doses. Corticosteroids produced naturally by the body, but they most often are used for their potent anti-inflammatory effects, particularly in those conditions in which the immune system plays an important role. Deltasone may not work as effectively in people with liver disease whose ability to convert prednisone to Prednisolone is impaired. Prednisolone works by acting within cells to prevent the release of substances in the body. Prednisone may interact with estrogens and phenytoin.