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Ann said: "Beta-blockers work by blocking beta receptors that are found in various parts of the body. Treatment with Propranolol, as this combination can cause severely high blood pressure and slow heart rate. Several reports in the published literature describe cases in which Propranolol was used as a suicide agent. The combination of Propranolol with thiazide-like diuretics and peripheral vasodilators has been shown to be compatible and generally more effective than Propranolol alone. Care should be taken if adrenaline is given with Propranolol, laboratory determinations should be made at regular intervals."
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